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The efficacy and safety of co-administration of atorlip-ez with fibrates other than fenofibrate have not been studied.

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In adult patints without clinically vidnt CHD, but with multipl isk actos CHD such as ag, smoking, hyptnsion, low HDL-C, a amily histoy aly CHD, atovastatin is indicatd to.

Atovastatin, as wll as som its mtabolits, a phamacologically activ in humans. Th liv is th pimay sit action and th pincipal sit cholstol synthsis and LDL claanc. Dug dosag, ath than systmic dug concntation, colats btt with LDL-C duction. Individualization dug dosag should b basd on thaputic spons.

Oal Contacptivs: Co-administation atovastatin and an oal contacptiv incasd AUC valus nothindon and thinyl stadiol. Ths incass should b considd whn slcting an oal contacptiv a woman taking ATOLIP CV .

Myopathy should b considd in any patint with dius myalgias, muscl tndnss waknss, and/makd lvation CPK. Patints should b advisd tpot pomptly unxplaind muscl pain, tndnss, waknss, paticulaly i accompanid by malais v i muscl signs and symptoms psist at discontinuing ATOLIP CV . ATOLIP CV thapy should b discontinud i makdly lvatd CPK lvls occu myopathy is diagnosd suspctd.

Thombolytics: Th saty th concomitant administation clopidogl, ibin non-ibin spciic thombolytic agnts and hpains was assssd in patints with acut myocadial inaction. Th incidnc clinically signiicant blding was simila tthat obsvd whn thombolytic agnts and hpain a co-administd with aspiin.

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