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What should I discuss with my healthcare provider before taking piroxicamFeldene

Stop taking piroxicam and seek medical attention or call your doctor at once if you have any of these serious side effects:

To minimize the potential risk for an adverse CV event in NSAID-treated patientsuse the lowest effective dose for the shortest duration possiblePhysicians and patients should remain alert for the development of such eventsthroughout the entire treatment courseeven in the absence of previous CV symptomsPatients should be informed about the symptoms of serious CV events and the steps to take if they occur.

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Increased risk of serious cardiovascular eventsincluding MIstrokeAvoid in recent MIsevere heart failureif necessarymonitorIncreased risk of serious GI adverse eventsincluding inflammationbleedingulcerationperforationHistory of ulcer disease and/or GI bleedingHypertensionmonitor BP closelyHepatic or renal impairmentDiscontinue if signs/symptoms of liver disease developor if abnormal LFTs persist or worsenDehydrationHypovolemiaAdvanced renal diseasenot recommendedHyperkalemiaCoagulation disordersMonitor CBCsblood chemistryhepaticrenaland ocular function in long-term therapyPre-existing asthmaCYP2C9 poor metabolizersMay mask signs of infection or feverDiscontinue at 1 st sign of rash or any other hypersensitivityElderlyDebilitatedLabordeliveryPregnancyCat.C1 st and 2 nd trimesterCat.D3 rd trimesteravoidNursing mothers.

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